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Modeling Pancreatic Cancer In Vivo

19 Mar 2010

Abstract excerpt

In the last 10 years, there has been a relative explosion of new rodent systems that recapitulate both genetic and cellular lesions that lead to the development of pancreatic cancer. These models now need to be considered when selecting an appropriate in vivo system to study disease etiology, cell signaling, and drug development. The majority of these evaluations have used transplantation of cancer cells and the...

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PMID: 20335777
DOI: 10.1097/mpa.0b013e3181c15619

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