Article
HDL as a Causal Factor in Atherosclerosis: Insights from Human Genetics.
Current atherosclerosis reports - 1 Dec 2016
Brunham Liam R
Abstract excerpt
High-density lipoprotein cholesterol (HDL-C) levels are inversely related to risk of atherosclerotic cardiovascular disease (ASCVD). However, the simplistic assumption that HDL-C levels directly and causally impact atherogenesis has been challenged in recent years. The purpose of this article is to review the current state of knowledge regarding genetically determined HDL-C levels and ASCVD risk and determine...
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