Article
Beyond the genetics of HDL: why is HDL cholesterol inversely related to cardiovascular disease?
Handbook of experimental pharmacology - 1 Jan 2015
Kuivenhoven J A, Groen A K
Abstract excerpt
There is unequivocal evidence that high-density lipoprotein (HDL) cholesterol levels in plasma are inversely associated with the risk of cardiovascular disease (CVD). Studies of families with inherited HDL disorders and genetic association studies in general (and patient) population samples have identified a large number of factors that control HDL cholesterol levels. However, they have not resolved why HDL...
Topics
- Animals
- Biomarkers
- Cardiovascular Diseases
- Cholesterol, HDL
- Genetic Predisposition to Disease
- Humans
- Phenotype
- Protective Factors
- Protein Conformation
- Risk Assessment
- Risk Factors