Article
The value of HDL genetics.
Current opinion in lipidology - 1 Aug 2008
Holleboom Adriaan G, Vergeer Menno, Hovingh G Kees, Kastelein John Jp, Kuivenhoven Jan Albert
Abstract excerpt
PURPOSE OF REVIEW: To review studies on hereditary disorders of high-density lipoprotein (HDL) metabolism and studies on HDL genetics in mice, which have both provided valuable insight into the pathways of this intriguing lipoprotein and moreover revealed targets to raise HDLc to reduce atherosclerosis. RECENT FINDINGS: To date, as many as 11 genes are considered key players in the synthesis, maturation,...
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