Article
Collective effects of common single nucleotide polymorphisms and genetic risk prediction in type 1 diabetes.
Clinical genetics - 1 May 2018
Gui Y, Lei X, Huang S
Abstract excerpt
Type 1 diabetes (T1D) is a common autoimmune disease and may be related to multiple genetic and environmental risk factors. Previous genetic studies have focused on looking for individual polymorphic risk variants. Here, we studied the overall levels of genetic diversity in T1D patients by making use of a previously published study including 1865 cases and 2828 reference samples with genotyping data for 500 K...
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