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Article

Cognitive impairment in Glucocerebrosidase (GBA)-associated PD: Not primarily associated with cerebrospinal fluid Abeta and Tau profiles.

Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2017

Lerche Stefanie, Schulte Claudia, Srulijes Karin, Pilotto Andrea, Rattay Tim W, Hauser Ann-Kathrin, Stransky Elke, Deuschle Christian, Csoti Ilona, Lachmann Ingolf, Zetterberg Henrik, Liepelt-Scarfone Inga, Gasser Thomas, Maetzler Walter, Berg Daniela, Brockmann Kathrin

Abstract excerpt

BACKGROUND: A proportion of idiopathic Parkinson's disease patients (PDidiopathic ) with dementia show altered CSF profiles of amyloid β (Aβ) and Tau. PD patients with Glucocerebrosidase (GBA) mutations (PDGBA ) present with even more cognitive decline than seen in PDidiopathic . OBJECTIVE: The objective of this study was to evaluate whether CSF profiles of Aβ and tau are associated with the prominent cognitive...

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Source

Identifiers

PMID: 29094781
DOI: 10.1002/mds.27199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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