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Article

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease.

Journal of the American Heart Association - 31 Oct 2017

Chan Kenneth, Pu Xiangyuan, Sandesara Pratik, Poston Robin N, Simpson Iain A, Quyyumi Arshed A, Ye Shu, Patel Riyaz S

Abstract excerpt

BACKGROUND: Genome-wide association studies identified ADAMTS7 as a risk locus for coronary artery disease (CAD). Functional studies suggest that ADAMTS7 may promote cellular processes in atherosclerosis. We sought to examine the association between genetic variation at ADAMTS7 and measures of atherosclerosis using histological, angiographic, and clinical outcomes data. METHODS AND RESULTS: The lead...

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Source

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Identifiers

PMID: 29089340
DOI: 10.1161/JAHA.117.006928
PMCID: PMC5721775

Genes

ADAMTS7
CAD

Provenance

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Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease.PMID 29089340Read ↗

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