Association of ADAMTS7 gene polymorphism with cardiovascular survival in coronary artery disease.

doi:10.1152/physiolgenomics.00059.2016

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Article

Association of ADAMTS7 gene polymorphism with cardiovascular survival in coronary artery disease.

Physiological genomics - 1 Nov 2016

Pereira A, Palma Dos Reis R, Rodrigues R, Sousa A C, Gomes S, Borges S, Ornelas I, Freitas A I, Guerra G, Henriques E, Rodrigues M, Freitas S, Freitas C, Brehm A, Pereira D, Mendonça M I

Abstract excerpt

Recent genetic studies have revealed an association between polymorphisms at the ADAMTS7 gene locus and coronary artery disease (CAD) risk. Functional studies have shown that a CAD-associated polymorphism (rs3825807) affects ADAMTS7 maturation and vascular smooth muscular cell (VSMC) migration. Here, we tested whether ADAMTS7 (A/G) SNP is associated with cardiovascular (CV) survival in patients with established...

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Identifiers

PMID: 27614204
DOI: 10.1152/physiolgenomics.00059.2016

Genes

ADAMTS7
CAD

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