Article
ADAMTS7 locus confers high cross-race risk for development of coronary atheromatous plaque.
Molecular genetics and genomics : MGG - 1 Feb 2016
You Ling, Tan Lun, Liu Lei, Shen Rufei, Chaugai Sandip, Wang Dao Wen, Cui Wei
Abstract excerpt
Genome-wide association studies of coronary artery disease (CAD) have recently identified a new susceptibility locus, ADAMTS7, in subjects of European ancestry. However, the significance of this locus in Chinese populations has not been identified. Therefore, this study was designed to evaluate the effect of rs3825807, a non-synonymous variant in the prodomain of the ADAMTS7 protease, on CAD risk and...
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