Article
ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.
Annals of medicine - 1 Jan 2009
Levula Mari, Airla Nina, Oksala Niku, Hernesniemi Jussi A, Pelto-Huikko Markku, Salenius Juha-Pekka, Zeitlin Rainer, Järvinen Otso, Huovila Ari-Pekka J, Nikkari Seppo T, Jaakkola Olli, Ilveskoski Erkki, Mikkelsson Jussi, Perola Markus, Laaksonen Reijo, Kytömäki Leena, Soini Juhani T, Kähönen Mika, Parkkinen Jyrki, Karhunen Pekka J, Lehtimäki Terho
Abstract excerpt
OBJECTIVE: Previously, we scanned all 23,000 human genes for differential expression between normal and atherosclerotic tissues and found the involvement of ADAM8. METHODS: We investigated the expression of ADAM8 mRNA and protein level in human atherosclerotic tissues and non-atherosclerotic internal thoracic arteries as well as the association of ADAM8 2662 T/G single nucleotide polymorphism (SNP) with the...
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