Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts.

Atherosclerosis - 1 Sept 2011

Raitoharju Emma, Seppälä Ilkka, Levula Mari, Kuukasjärvi Pekka, Laurikka Jari, Nikus Kjell, Huovila Ari-Pekka J, Oksala Niku, Klopp Norman, Illig Thomas, Laaksonen Reijo, Karhunen Pekka J, Viik Jari, Lehtinen Rami, Pelto-Huikko Markku, Tarkka Matti, Kähönen Mika, Lehtimäki Terho

Abstract excerpt

OBJECTIVE: The single nucleotide polymorphism (SNP) rs2995300 in the metalloproteinase-disintegrin gene ADAM8 has been shown to affect the areas of complicated coronary plaques and the risk of fatal myocardial infarction (MI) in men. This study was set up to further investigate the role of ADAM8 in MI. AIM: To investigate the possible association of the ADAM8 SNPs rs2995300 and rs2275725 with ADAM8 mRNA levels,...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to Cohort Studies
Share to Enzyme-Linked Immunosorbent Assay
Share to Finland
Share to Gene Expression Regulation
Share to Membrane Proteins
Share to Myocardial Infarction
Share to Risk

Source

Identifiers

PMID: 21640993
DOI: 10.1016/j.atherosclerosis.2011.05.005

Genes

ADAM8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts.PMID 21640993Read ↗

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.Semantic proximity Read ↗

ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant.Semantic proximity Read ↗

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease.Semantic proximity Read ↗

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.Semantic proximity Read ↗

Association of polymorphisms in ADAMTS-7 gene with the susceptibility to coronary artery disease - a systematic review and meta-analysis.Semantic proximity Read ↗

Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarctionSemantic proximity Read ↗

[Genes for Fibrogenesis in the Determination of Susceptibility to Myocardial Infarction].Semantic proximity Read ↗

ADAMTS7 locus confers high cross-race risk for development of coronary atheromatous plaque.Semantic proximity Read ↗

The rs3825807 Polymorphism of ADAMTS7 as a Potential Genetic Marker for Myocardial Infarction in Slovenian Subjects with Type 2 Diabetes Mellitus.Semantic proximity Read ↗

Genetic Predisposition to Early Myocardial InfarctionSemantic proximity Read ↗

Association of ADAMTS7 gene polymorphism with cardiovascular survival in coronary artery disease.Semantic proximity Read ↗

A functional polymorphism in ADAMTS7 3'-UTR abrogates miR-654-5p-mediated ADAMTS7 expression suppression and increases the incidence, short-term outcome, and recurrence of large artery atherosclerotic stroke among southern Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.