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Article

Host genotype and time dependent antigen presentation of viral peptides: predictions from theory.

Scientific reports - 30 Oct 2017

Eccleston R Charlotte, Coveney Peter V, Dalchau Neil

Abstract excerpt

The rate of progression of HIV infected individuals to AIDS is known to vary with the genotype of the host, and is linked to their allele of human leukocyte antigen (HLA) proteins, which present protein degradation products at the cell surface to circulating T-cells. HLA alleles are associated with Gag-specific T-cell responses that are protective against progression of the disease. While Pol is the most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 29084996
DOI: 10.1038/s41598-017-14415-8
PMCID: PMC5662608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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