Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.

doi:10.1371/journal.pone.0187205

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Article

Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.

PloS one - 1 Jan 2017

Coignet Marie V, Zirpoli Gary Robert, Roberts Michelle R, Khoury Thaer, Bandera Elisa V, Zhu Qianqian, Yao Song

Abstract excerpt

Reproductive aging phenotypes, including age at menarche (AM) and age at natural menopause (ANM), are well-established risk factors for breast cancer. In recent years, many genetic variants have been identified in association with AM and ANM in genome-wide association studies among European populations. Using data from the Women's Circle of Health Study (WCHS) of 1,307 European-American (EA) and 1,365...

Topics

Adult
Black or African American
Aged
Aging
Breast Neoplasms
Female
Genetic Predisposition to Disease
Genetic Variation
Humans
Menarche
Menopause

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Polymorphism, Single Nucleotide

Reproduction

Risk Factors

White People

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29073238
DOI: 10.1371/journal.pone.0187205
PMCID: PMC5658184

Genes

MCM8
RXRG
TMEM18

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