Article
Postimplantation Mga expression and embryonic lethality of two gene-trap alleles.
Gene expression patterns : GEP - 1 Jan 2018
Burn Sally F, Washkowitz Andrew J, Gavrilov Svetlana, Papaioannou Virginia E
Abstract excerpt
BACKGROUND: The dual-specificity T-box/basic helix-loop-helix leucine zipper transcription factor MGA is part of the MAX-interacting network of proteins. In the mouse, MGA is necessary for the survival of the pluripotent epiblast cells of the peri-implantation embryo and a null, gene-trap allele MgaGt results in embryonic lethality shortly after implantation. We have used this allele to document expression of Mga...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.