Article
Restricted expression of mouse GCMa/Gcm1 in kidney and thymus.
Mechanisms of development - 1 Oct 2002
Hashemolhosseini Said, Hadjihannas Michel, Stolt Claus C, Haas Christian S, Amann Kerstin, Wegner Michael
Abstract excerpt
Mouse Glial Cells Missing a (mGCMa) belongs to a small family of transcription factors named after the prototypical GCM from Drosophila. mGCMa was expected to regulate gliogenesis, but instead found to be primarily expressed during development in trophoblasts of chorion and labyrinth. Its deletion causes abnormal placental labyrinth formation and results in embryonic lethality. Here we identify kidney and thymus...
Topics
- Animals
- Blotting, Western
- DNA-Binding Proteins
- Electrophoresis, Polyacrylamide Gel
- Gene Deletion
- Gene Expression Regulation, Developmental
- Genotype
- Kidney
- Mice
- Neuropeptides
- Thymus Gland