Article
The tbx/bHLH transcription factor mga regulates gata4 and organogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2010
Rikin Amir, Evans Todd
Abstract excerpt
The mga gene encodes a unique transcription factor containing both TBOX and bHLHzip DNA-binding domains. Here we describe the structure, expression pattern, and loss-of-function phenotype for zebrafish mga. The mga gene is conserved with mammalian homologs for both DNA-binding domains. It is expressed maternally, and subsequently in the developing brain, heart, and gut, and its depletion causes morphogenetic...
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