Article
Immunosuppressive effect of renal cell carcinoma on phenotype and function of dendritic cells.
International urology and nephrology - 1 May 2014
Teng Lichen, Chen Yongsheng, Ding Dexin, Dai Hongshuang, Liu Guobin, Li Changfu
Abstract excerpt
Dendritic cells (DCs) play an important role in anti-renal cell carcinoma (RCC) immunity. The aim of the study was to investigate effect of mimic RCC microenvironment on phenotype and function of DCs. We isolated conditioned media (CM) from supernatants of culturing RCC cells and adjacent non-RCC cells in patients. CD14+ monocytes were obtained from healthy donors. The monocytes derived DCs were treated by RCC CM...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
