Article
Variants of katG, inhA and nat genes are not associated with mutations in efflux pump genes (mmpL3 and mmpL7) in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from India.
Tuberculosis (Edinburgh, Scotland) - 1 Dec 2017
Unissa A Nusrath, Dusthackeer V N Azger, Kumar Micheal Prem, Nagarajan P, Sukumar S, Kumari V Indira, Lakshmi A Ramya, Hanna L E
Abstract excerpt
To understand the impact of efflux pump genes such as mmpL3 and mmpL7 on isoniazid (INH) resistance and to correlate with presence or absence of mutations in essential genes of INH resistance (katG, inhA, and nat) in clinical isolates of Mycobacterium tuberculosis (M. tuberculosis). One hundred (75 resistant and 25 sensitive) clinical isolates of M. tuberculosis from India were selected for the study. The...
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