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Article

Blocking probe as a potential tool for detection of single nucleotide DNA mutations: design and performance.

Nanoscale - 2 Nov 2017

Aboudzadeh M Ali, Sanromán-Iglesias M, Lawrie C H, Grzelczak M, Liz-Marzán L M, Schäfer T

Abstract excerpt

Developing strategies to detect single nucleotide DNA mutations associated with treatment decisions in cancer patients from liquid biopsies is a rapidly emerging area of personalized medicine that requires high specificity. Here we report how to design an easy enzyme-free approach that could create a platform for detection of L858R mutation of EGFR that is a predictive biomarker of tyrosine kinase treatment in...

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PMID: 29043363
DOI: 10.1039/c7nr06675a

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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