Article
Correlation analysis of the HLA-DPB1*05:01 and BTNL2 genes within the histocompatibility complex region with a clinical phenotype of psoriasis vulgaris in the Chinese Han population.
The journal of gene medicine - 1 Sept 2017
Guo Huimin, Huang Yong, Wu Juan, Zheng Xiaodong, Ye Lei, Huang Hequn, Wang Wenjun, Zhen Qi, Wu Jing, Qian Wenjun, Cheng Hui, Fan Xing, Zhang Xuejun
Abstract excerpt
BACKGROUND: The human major histocompatibility complex (MHC) is known to be highly polymorphic and has been identified to be associated with numerous diseases. The HLA-DPB1 and BTNL2 genes were associated with psoriasis for the first time. The present study aims to investigate the relevance of the HLA-DPB1 and BTNL2 genes with respect to clinical phenotypes of psoriasis vulgaris (PV). METHODS: To investigate...
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