Article
Association of the novel susceptible locus rs9266150 with clinical features of psoriasis vulgaris in the Chinese Han population.
Experimental dermatology - 1 Jul 2018
Wu Juan, Huang Yan, Guo Huimin, Ye Lei, Huang Yong, Huang Hequn, Qian Wenjun, Zhang Xuelei, Wang Wenjun, Zheng Xiaodong, Zhang Xuejun, Fan Xing, Liu Jianjun, Yang Sen
Abstract excerpt
Psoriasis is a chronic multifactorial disease and is considered to be strongly associated with the major histocompatibility complex (MHC) region. We have discovered an independent, novel and susceptible psoriasis risk HLA loci, rs9266150; P = 4.52 × 10-9 for the first time. In this study, we aimed to verify the relationship between the susceptible locus and the subphenotypes of psoriasis vulgaris (PV), including...
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