Association Study and Fine-Mapping Major Histocompatibility Complex Analysis of Pemphigus Vulgaris in a Han Chinese Population.

doi:10.1016/j.jid.2018.05.011

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Article

Association Study and Fine-Mapping Major Histocompatibility Complex Analysis of Pemphigus Vulgaris in a Han Chinese Population.

The Journal of investigative dermatology - 1 Nov 2018

Gao Jinping, Zhu Caihong, Zhang Yaohua, Sheng Yujun, Yang Fanping, Wang Wenjun, Qian Wenjun, Chen Sheng'an, Zhu Qinyuan, Zuo Xianbo, Tang Huayang, Tang Xianfa, Li Yang, Cheng Hui, Zhou Fusheng, Liu Shengxiu, Chen Gang, Zheng Xiaodong, Zhu Zhengwei, Wang Zaixing, Yang Sen, Luo Xiaoqun, Ye Dongqing, Zhang Xuejun, Sun Liangdan

Abstract excerpt

To identify possible additional genetic susceptibility loci for pemphigus vulgaris (PV), we performed a genome-wide association study of 240 PV patients and 1,031 control individuals, and we selected the top single nucleotide polymorphisms for replication in independent samples, with 252 patient samples and 1,852 control samples. We identified rs11218708 (P = 3.1 × 10-8, odds ratio = 1.54) at chromosome locus...

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PMID: 29857070
DOI: 10.1016/j.jid.2018.05.011

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TAP2

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