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Article

The current landscape of psoriasis genetics in 2020.

Journal of dermatological science - 1 Jul 2020

Ogawa Kotaro, Okada Yukinori

Abstract excerpt

Psoriasis is an immune-mediated disease associated with skin and joint inflammation that affects large proportions of populations worldwide. It is a heritable disease: individuals' genetic backgrounds modulate their susceptibility. In genetics, multiple human leukocyte antigen (HLA) genes are most strongly associated with the risk of psoriasis, especially HLA-C*06:02. In the last 10 years, large-scale genome-wide...

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PMID: 32536600
DOI: 10.1016/j.jdermsci.2020.05.008

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