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Helicobacter pylori Vacuolating Toxin and Gastric Cancer.

Toxins - 12 Oct 2017

McClain Mark S, Beckett Amber C, Cover Timothy L

Abstract excerpt

Helicobacter pylori VacA is a channel-forming toxin unrelated to other known bacterial toxins. Most H. pylori strains contain a vacA gene, but there is marked variation among strains in VacA toxin activity. This variation is attributable to strain-specific variations in VacA amino acid sequences, as well as variations in the levels of VacA transcription and secretion. In this review, we discuss epidemiologic...

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Identifiers

PMID: 29023421
DOI: 10.3390/toxins9100316
PMCID: PMC5666363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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