Article
Clinical relevance of Helicobacter pylori vacA and cagA genotypes in gastric carcinoma.
Best practice & research. Clinical gastroenterology - 1 Dec 2014
Ferreira Rui M, Machado José C, Figueiredo Ceu
Abstract excerpt
Helicobacter pylori infection is the major etiological factor of gastric carcinoma. This disease is the result of a long, multistep, and multifactorial process, which occurs only in a small proportion of patients infected with H. pylori. Gastric carcinoma development is influenced by host genetic susceptibility factors, environmental factors, and H. pylori virulence. H. pylori is genetically highly variable, and...
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