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Article

Relationship between vacA Types and Development of Gastroduodenal Diseases.

Toxins - 9 Jun 2016

Thi Huyen Trang Tran, Thanh Binh Tran, Yamaoka Yoshio

Abstract excerpt

The Helicobacter pylori vacuolating cytotoxin (VacA) is a secreted pore-forming toxin and a major virulence factor in the pathogenesis of H. pylori infection. While VacA is present in almost all strains, only some forms are toxigenic and pathogenic. While vacA and its genotypes are considered as markers of H. pylori-related diseases or disorders, the pathophysiological mechanisms of VacA and its genotypes remain...

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Source

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Identifiers

PMID: 27294955
DOI: 10.3390/toxins8060182
PMCID: PMC4926148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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