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Article

Cloned low metastatic variants from human lung carcinoma metastases.

Anticancer research - 1 Jan 2000

Varki N M, Tseng A, Vu T P, Estes L A

Abstract excerpt

Clonal subpopulations of neoplastic cells were derived, in soft agar, from the spontaneously metastazing variant (MV522) of a human lung carcinoma cell line. The ability of these clones to spontaneously metastasize from subcutaneous sites in athymic mice was then tested. A variation in metastatic ability was expected with the derivation of some low metastatic clones and some high metastatic ones. However, all of...

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PMID: 2369080

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