Article
Cloned low metastatic variants from human lung carcinoma metastases.
Anticancer research - 1 Jan 2000
Varki N M, Tseng A, Vu T P, Estes L A
Abstract excerpt
Clonal subpopulations of neoplastic cells were derived, in soft agar, from the spontaneously metastazing variant (MV522) of a human lung carcinoma cell line. The ability of these clones to spontaneously metastasize from subcutaneous sites in athymic mice was then tested. A variation in metastatic...
Topics
- Animals
- Cell Division
- Cell Line
- Clone Cells
- Female
- Genetic Variation
- Humans
- Isoenzymes
- Karyotyping
- Lung Neoplasms
- Mice
- Mice, Nude
- Neoplasm Metastasis
- Neoplasm Transplantation
- Transplantation, Heterologous
- Tumor Cells, Cultured