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Article

CDH1 mutation screen in a BRCA1/2-negative familial breast-/ovarian cancer cohort.

Archives of gynecology and obstetrics - 1 Jan 2018

Stuebs Frederik, Heidemann Simone, Caliebe Almuth, Mundhenke Christoph, Arnold Norbert

Abstract excerpt

PURPOSE: Mutations in the CDH1 gene are linked both to diffuse gastric cancer and invasive lobular carcinoma (ILC). A high mutation rate is found in families fulfilling the diagnostic criteria for hereditary diffuse gastric cancer. Aim of this study was to clarify whether or not there is a significant contribution of CDH1 mutations in hereditary breast-/ovarian cancer (HBOC). METHODS: Ninety-seven unrelated...

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Source

Identifiers

PMID: 28993866
DOI: 10.1007/s00404-017-4551-1

Genes

CDH1
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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