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Article

Sequential acquisition of mutations in myelodysplastic syndromes.

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2017

Makishima Hideki

Abstract excerpt

Recent progress in next-generation sequencing technologies allows us to discover frequent mutations throughout the coding regions of myelodysplastic syndromes (MDS), potentially providing us with virtually a complete spectrum of driver mutations in this disease. As shown by many study groups these days, such driver mutations are acquired in a gene-specific fashion. For instance, DDX41 mutations are observed in...

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Source

Identifiers

PMID: 28978821
DOI: 10.11406/rinketsu.58.1828

Genes

DDX41
FLT3
GATA2
NRAS
RUNX1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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