[Clonal evolution of myelodysplastic syndromes].

Abstract excerpt

By intensive efforts of sequencing a large number of genomes from patients with myelodysplastic syndromes (MDS), a comprehensive registry of driver mutations repeatedly found in MDS patients has been identified, providing us with a virtually complete spectrum of driver mutations in this disease. Importantly, significant correlations between driver mutations have been revealed, suggesting that some combinations of...

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