Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myelodysplastic syndromes: Biological and therapeutic consequences of the evolving molecular aberrations landscape.

Neoplasia (New York, N.Y.) - 1 Nov 2021

Schwind Sebastian, Jentzsch Madlen, Kubasch Anne Sophie, Metzeler Klaus H, Platzbecker Uwe

Abstract excerpt

Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders with heterogeneous presentation, ranging from indolent disease courses to aggressive diseases similar to acute myeloid leukemia (AML). Approximately 90% of MDS patients harbor recurrent mutations , which - with the exception of mutated SF3B1 -have not (yet) been included into the diagnostic criteria or risk stratification for MDS. Accumulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Myelodysplastic Syndromes

Share to Prognosis

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 34601234
DOI: 10.1016/j.neo.2021.09.002
PMCID: PMC8495032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myelodysplastic syndromes: Biological and therapeutic consequences of the evolving molecular aberrations landscape.PMID 34601234Read ↗

Unraveling the molecular pathophysiology of myelodysplastic syndromes.Semantic proximity Read ↗

The Molecular Pathology of Myelodysplastic Syndrome.Semantic proximity Read ↗

The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia.Semantic proximity Read ↗

Molecular pathophysiology of myelodysplastic syndromes.Semantic proximity Read ↗

Clinical Implications of Genetic Mutations in Myelodysplastic Syndrome.Semantic proximity Read ↗

The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome.Semantic proximity Read ↗

Navigating the contested borders between myelodysplastic syndrome and acute myeloid leukemiaSemantic proximity Read ↗

Genetic and molecular characterization of myelodysplastic syndromes and related myeloid neoplasms.Semantic proximity Read ↗

Have we reached a molecular era in myelodysplastic syndromes?Semantic proximity Read ↗

Evolutionary trajectories of myelodysplastic syndromes/neoplasms.Semantic proximity Read ↗

The genetics of myelodysplastic syndromes and the opportunities for tailored treatmentsSemantic proximity Read ↗

Myelodysplastic syndromes: molecular pathogenesis and genomic changes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.