Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of myelodysplastic syndromes: new insights.

Hematology. American Society of Hematology. Education Program - 1 Jan 2011

Graubert Timothy, Walter Matthew J

Abstract excerpt

Myelodysplastic syndromes (MDS) are a heterogenous group of hematologic malignancies characterized by clonal expansion of BM myeloid cells with impaired differentiation. The identification of recurrent mutations in MDS samples has led to new insights into the pathophysiology of these disorders. Of particular interest is the recent recognition that genes involved in the regulation of histone function (EZH2, ASXL1,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to DNA Methylation
Share to ASXL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IDH2 gene

Share to Haploinsufficiency

Share to Karyotyping

Share to Mutation

Share to Myelodysplastic Syndromes

Source

Identifiers

PMID: 22160087
DOI: 10.1182/asheducation-2011.1.543

Genes

ASXL1
IDH1
IDH2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of myelodysplastic syndromes: new insights.PMID 22160087Read ↗

The Genetics of Myelodysplastic Syndromes: Clinical Relevance.Semantic proximity Read ↗

Integrating genetics and epigenetics in myelodysplastic syndromes: advances in pathogenesis and disease evolutionSemantic proximity Read ↗

Genetic basis of myelodysplastic syndromes.Semantic proximity Read ↗

Genetics of MDSSemantic proximity Read ↗

The genetic basis of myelodysplasia and its clinical relevance.Semantic proximity Read ↗

Mutations of myelodysplastic syndromes (MDS): An update.Semantic proximity Read ↗

Genetics factors associated with myelodysplastic syndromes.Semantic proximity Read ↗

The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.Semantic proximity Read ↗

Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview.Semantic proximity Read ↗

The genetics of myelodysplastic syndromes and the opportunities for tailored treatmentsSemantic proximity Read ↗

Update on cytogenetic and molecular changes in myelodysplastic syndromes.Semantic proximity Read ↗

Genetics of Myelodysplastic SyndromesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.