Article
[Predisposition and progression of myelodysplastic syndromes].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2021
Makishima Hideki
Abstract excerpt
Recent advances in sequencing technologies have increased the detection rate for identifying germline mutations that predispose an individual to various myeloid neoplasms and somatic mutations acquired during progression from myelodysplastic syndromes (MDS) to acute myeloid leukemia (AML). In addition to pediatric subjects, adult patients were analyzed in order to obtain a complete spectrum of driver mutations in...
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