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Article

The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment.

Pharmacogenomics - 1 Oct 2017

Levran Orna, Peles Einat, Randesi Matthew, da Rosa Joel Correa, Adelson Miriam, Kreek Mary Jeanne

Abstract excerpt

AIM: This study assesses whether opioid-related gene variants contribute to reduced vulnerability to relapse to heroin in persons who are not treated with μ-opioid receptor agonist. METHODS: Genotypes of 71 SNPs, in nine genes, were analyzed for association with long-term abstinence in former heroin-dependents of European/Middle Eastern ancestry, either without agonist treatment (n = 129) or in methadone...

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Share to Analgesics, Opioid
Share to OPRM1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Heroin Dependence

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Opioid, mu

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Source

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Identifiers

PMID: 28976288
DOI: 10.2217/pgs-2017-0092
PMCID: PMC7270956

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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