Article
OPRM1 rs1799971 polymorphism and opioid dependence: evidence from a meta-analysis.
Pharmacogenomics - 1 May 2013
Haerian Batoul Sadat, Haerian Monir Sadat
Abstract excerpt
The OPRM1 gene encodes the µ-opioid receptor, which is the primary site of action of most opioids. Several studies and three meta-analyses have examined a possible link between the exonic OPRM1 A118G (rs1799971) polymorphism and opioid dependence; however, results have been inconclusive. Therefore, a systematic review and meta-analysis have been carried out to examine whether this polymorphism is associated with...
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