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Article

Genetic variations in genes of the stress response pathway are associated with prolonged abstinence from heroin.

Pharmacogenomics - 1 Mar 2018

Levran Orna, Peles Einat, Randesi Matthew, Correa da Rosa Joel, Shen Pei-Hong, Rotrosen John, Adelson Miriam, Kreek Mary Jeanne

Abstract excerpt

AIM: This study assesses whether genetic variants in stress-related genes are associated with prolonged abstinence from heroin in subjects that are not in long-term methadone treatment. METHODS: Frequencies of 117 polymorphisms in 30 genes were compared between subjects with history of heroin addiction, either without agonist treatment (n = 129) or in methadone maintenance treatment (n = 923). RESULTS: SNP rs1500...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29465008
DOI: 10.2217/pgs-2017-0179
PMCID: PMC5941712

Genes

CRHBP

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