Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.

The Journal of cell biology - 6 Nov 2017

Salas-Pino Silvia, Gallardo Paola, Barrales Ramón R, Braun Sigurd, Daga Rafael R

Abstract excerpt

Kinetochores (KTs) are large multiprotein complexes that constitute the interface between centromeric chromatin and the mitotic spindle during chromosome segregation. In spite of their essential role, little is known about how centromeres and KTs are assembled and how their precise stoichiometry is regulated. In this study, we show that the nuclear pore basket component Alm1 is required to maintain both the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to Chromosome Segregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Fungal

Share to Endopeptidases

Share to Kinetochores

Share to Nuclear Envelope

Share to Proteolysis

Share to Schizosaccharomyces pombe Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28974540
DOI: 10.1083/jcb.201612194
PMCID: PMC5674884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.PMID 28974540Read ↗

Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instabilitySemantic proximity Read ↗

The nuclear pore complex-associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly.Semantic proximity Read ↗

Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mitotic Nuclear Envelope Breakdown and Spindle Nucleation Are Controlled by Interphase Contacts between Centromeres and the Nuclear Envelope.Semantic proximity Read ↗

Nuclear envelope assembly defects link mitotic errors to chromothripsisSemantic proximity Read ↗

Fission yeast Pcp1 links polo kinase-mediated mitotic entry to gamma-tubulin-dependent spindle formation.Semantic proximity Read ↗

Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle.Semantic proximity Read ↗

The 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin.Semantic proximity Read ↗

Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint.Semantic proximity Read ↗

Dynamic localization of the chromosomal passenger complex in trypanosomes is controlled by the orphan kinesins KIN-A and KIN-BSemantic proximity Read ↗

A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytesSemantic proximity Read ↗

Endosome-generated interior actin network regulates mitotic fidelity and organelle homeostasis downstream of P-cadherinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.