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Article

The 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin.

Nature communications - 7 Apr 2014

Kitagawa Teppei, Ishii Kojiro, Takeda Kojiro, Matsumoto Tomohiro

Abstract excerpt

CENP-A, a variant of histone H3, is incorporated into centromeric chromatin and plays a role during kinetochore establishment. In fission yeast, the localization of CENP-A is limited to a region spanning 10-20 kb of the core domain of the centromere. Here, we report a mutant (rpt3-1) in which this region is expanded to 40-70 kb. Likely due to abnormal distribution of CENP-A, this mutant exhibits chromosome...

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PMID: 24710126
DOI: 10.1038/ncomms4597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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