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Article

Endosome-generated interior actin network regulates mitotic fidelity and organelle homeostasis downstream of P-cadherin

2026-04-27

Abstract excerpt

<title>Abstract</title> <p>Accurate chromosome segregation during somatic cell division depends on precise assembly of the mitotic spindle, a process traditionally regarded as microtubule-centric1,2. Recent works in acentrosomal systems have implicated actin in spindle function3,4, but whether spindle-associated actin is a broader feature of centrosomal mitosis remains unclear1. Here we show that the mitotic spin...

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Literature Corpus work
2e1f8fc3-3638-5974-8c8f-b0492b694992
DOI
10.21203/rs.3.rs-9256156/v1
Open publication

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Endosome-generated interior actin network regulates mitotic fidelity and organelle homeostasis downstream of P-cadherinDOI 10.21203/rs.3.rs-9256156/v1
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