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Article

Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint.

The Journal of cell biology - 1 Jun 2020

Jackman Mark, Marcozzi Chiara, Barbiero Martina, Pardo Mercedes, Yu Lu, Tyson Adam L, Choudhary Jyoti S, Pines Jonathon

Abstract excerpt

How the cell rapidly and completely reorganizes its architecture when it divides is a problem that has fascinated researchers for almost 150 yr. We now know that the core regulatory machinery is highly conserved in eukaryotes, but how these multiple protein kinases, protein phosphatases, and ubiquitin ligases are coordinated in space and time to remodel the cell in a matter of minutes remains a major question....

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Identifiers

PMID: 32236513
DOI: 10.1083/jcb.201907082
PMCID: PMC7265330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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