Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimating time of HIV-1 infection from next-generation sequence diversity

2 Oct 2017

Abstract excerpt

Estimating the time since infection (TI) in newly diagnosed HIV-1 patients is challenging, but important to understand the epidemiology of the infection.Here we explore the utility of virus diversity estimated by next-generation sequencing (NGS) as novel biomarker by using a recent genome-wide longitudinal dataset obtained from 11 untreated HIV-1-infected patients with known dates of infection.The results were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Phylogenetic Studies
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28968389
DOI: 10.1371/journal.pcbi.1005775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimating time of HIV-1 infection from next-generation sequence diversityPMID 28968389Read ↗

Estimating time of HIV-1 infection from next-generation sequence diversitySemantic proximity Read ↗

HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection.Semantic proximity Read ↗

Genetic Diversity From Proviral DNA as a Proxy for Time Since HIV-1 Infection.Semantic proximity Read ↗

HIV-1 genetic diversity and divergence and its correlation with disease progression among antiretroviral naïve recently infected individuals.Semantic proximity Read ↗

Estimating HIV-1 Viremic Time From Reservoir Sequence Diversity With Uncertainty Quantification.Semantic proximity Read ↗

Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load.Semantic proximity Read ↗

Long-Read Deep Sequencing Reveals High Rates of Multilineage Transmission and Rapid Viral Population Changes in Acute HIV InfectionSemantic proximity Read ↗

Use of a high resolution melting (HRM) assay to compare gag, pol, and env diversity in adults with different stages of HIV infection.Semantic proximity Read ↗

Prediction of recent HIV-1 infections using Shannon entropy analysis of HIV-1 group-specific antigen protein sequence.Semantic proximity Read ↗

Factors influencing estimates of HIV-1 infection timing using BEAST.Semantic proximity Read ↗

Using HIV-1 sequence variability to explore virus biology.Semantic proximity Read ↗

Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing dataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.