Article
APOBEC: From mutator to editor.
Journal of genetics and genomics = Yi chuan xue bao - 20 Sept 2017
Yang Bei, Li Xiaosa, Lei Liqun, Chen Jia
Abstract excerpt
APOBECs (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) are a family of cytidine deaminases that prefer single-stranded nucleic acids as substrates. Besides their physiological functions, APOBEC family members have been found to cause hypermutations of cancer genomes, which could be correlated with cancer development and poor prognosis. Recently, APOBEC family members have been combined with...
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