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Article

The AID/APOBEC family of nucleic acid mutators

1 Jan 2008

Abstract excerpt

The AID/APOBECs, a group of cytidine deaminases, represent a somewhat unusual protein family that can insert mutations in DNA and RNA as a result of their ability to deaminate cytidine to uridine. The ancestral AID/APOBECs originated from a branch of the zinc-dependent deaminase superfamily at the beginning of the vertebrate radiation. Other members of the family have arisen in mammals and present a history of...

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PMID: 18598372
DOI: 10.1186/gb-2008-9-6-229

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