Article
GAB2 Amplification in Squamous Cell Lung Cancer of Non-Smokers.
Journal of Korean medical science - 1 Nov 2017
Park Yu Rang, Bae Soo Hyeon, Ji Wonjun, Seo Eul Ju, Lee Jae Cheol, Kim Hyeong Ryul, Jang Se Jin, Choi Chang Min
Abstract excerpt
Lung squamous cell cancer (SCC) is typically found in smokers and has a very low incidence in non-smokers, indicating differences in the tumor biology of lung SCC in smokers and non-smokers. However, the specific mutations that drive tumor growth in non-smokers have not been identified. To identify mutations in lung SCC of non-smokers, we performed a genetic analysis using arrays comparative genomic hybridization...
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