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Article

Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms.

Oncotarget - 25 Oct 2016

Freeman Joshua R, Chu Su, Hsu Thomas, Huang Yen-Tsung

Abstract excerpt

Tobacco smoke is a well-established lung cancer carcinogen. We hypothesize that epigenetic processes underlie carcinogenesis. The objective of this study is to examine the effects of smoke exposure on DNA methylation to search for novel susceptibility loci. We obtained epigenome-wide DNA methylation data from lung adenocarcinoma (LUAD) and lung squamous cell (LUSC) tissues in The Cancer Genome Atlas (TCGA). We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27602958
DOI: 10.18632/oncotarget.11831
PMCID: PMC5342499

Genes

NFIX
SMUG1
WWTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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