Article
Genomic variations in the counterpart normal controls of lung squamous cell carcinomas.
Frontiers of medicine - 1 Jun 2018
Zhang Dalin, Qu Liwei, Zhou Bo, Wang Guizhen, Zhou Guangbiao
Abstract excerpt
Lung squamous cell carcinoma (LUSC) causes approximately 400 000 deaths each year worldwide. The occurrence of LUSC is attributed to exposure to cigarette smoke, which induces the development of numerous genomic abnormalities. However, few studies have investigated the genomic variations that occur only in normal tissues that have been similarly exposed to tobacco smoke as tumor tissues. In this study, we...
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