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Article

Enhanced immune response induced by P5 HER2/neu-derived peptide-pulsed dendritic cells as a preventive cancer vaccine.

Journal of cellular and molecular medicine - 1 Jan 2018

Gholizadeh Zahra, Tavakkol-Afshari Jalil, Nikpoor Amin Reza, Jalali Seyed Amir, Jaafari Mahmoud Reza

Abstract excerpt

Dendritic cells are special and powerful antigen-presenting cells that can induce primary immune responses against tumour-associated antigens. They can present antigens via both MHC-I and MHC-II, so they have the ability to stimulate both cytotoxic T lymphocytes and T helper cells. Furthermore, CD8+ cytotoxic T lymphocytes require activation by CD4+ T cells. This requires a CD4+ T cell activator molecule, of...

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Identifiers

PMID: 28944998
DOI: 10.1111/jcmm.13343
PMCID: PMC5742681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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