Article
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model
1 Dec 2012
Abstract excerpt
DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal and dermal layers of the skin are characterized by an abundance of antigen-presenting cells (APCs). The aim of our study was to compare tumor protection as obtained by two different methods of intradermal DNA...
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