Article
Generation of multiple peptide cocktail-pulsed dendritic cells as a cancer vaccine.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Lee Hyun-Ju, Choi Nu-Ri, Vo Manh-Cuong, Hoang My-Dung, Lee Youn-Kyung, Lee Je-Jung
Abstract excerpt
Cancer immunotherapy based on dendritic cell (DC) vaccination has promising alternatives for the treatment of cancer. A central tenet of DC-based cancer immunotherapy is the generation of antigen-specific cytotoxic T lymphocyte (CTL) response. Tumor-associated antigens (TAA) and DC play pivotal roles in this process. DCs are well known to be the most potent antigen-presenting cells and have the most powerful...
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