Article
A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study.
Scientific reports - 22 Sept 2017
Hauer Allard J, Pulit Sara L, van den Berg Leonard H, de Bakker Paul I W, Veldink Jan H, Ruigrok Ynte M
Abstract excerpt
We aimed to replicate reported associations of 10 SNPs at eight distinct loci with overall ischemic stroke (IS) and its subtypes in an independent cohort of Dutch IS patients. We included 1,375 IS patients enrolled in a prospective multicenter hospital-based cohort in the Netherlands, and 1,533 population-level controls of Dutch descent. We tested these SNPs for association with overall IS and its subtypes (large...
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